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Protective Effects of Radaway Radioprotection Capsule on Radition Injured Mice |
ZHAO Cui-Xia, YUAN Xue-Fen, SUN Li, WANG Xiao-Dan, XIE Tao |
Liaoning Center for Disease Control and Prevention, Shenyang 110005 China |
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Abstract Objective To observe the protective effects of Radaway radioprotection capsule on radition injured mice. Methods 120 female Kunming mice were randomly divided into 3 groups by the processing as peripheral white blood cell count(group I), marrow cell micronuclei detection(group Ⅱ), and bone marrow DNA count(group Ⅲ). And for each group, mice were further partitioned into low,middle and high dosage groups and radiation control group. The mice were all exposed by 3Gy radiation. Results The peripheral white blood cell level on the 14th day after radiation in three dose groups were all significantly higher than that of radiation control group. On the 3rd day after radiation,comparing with radiation control group micronucleus rate of marrow cells in middle and low dose groups was significantly lower,DNA count in bone marrow in low dose group was significantly higher. Conclutions Radaway radioprotection capsule has significantly protective effects on γ-ray radiation injuries of mice.
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Received: 07 March 2012
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