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| Effects of BSH on the Proliferation of Cells Irradiated by γ-Ray |
| QIAN Tian-tian, HE Ying, WANG Qing-rong, CHEN Wei, SHEN Xian-rong |
| Naval Medical Research Institute, Shanghai 200433 China |
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Abstract Objective To study the protective effect of BSH on the proliferation of Hela and HIEC cells irradiated by γ-ray. Methods Hela and HIEC cells which were given BSH,were exposed to 137Cs γ-ray one time with the different doses (1, 2, 3, 4, 6, 8 Gy) at the dose rate of 0.8 Gy/min. The proliferation of cells were measured by MTT assay and cell clone formation assay. Results MTT assay showed that BSH has a significant protective effect on cells at the concentration of 0.0036 mg/ml to 0.1150 mg/ml. Clone formation assay showed that the protective effect of BSH (0.060mg/ml) was different when cells exposed to different doses. Conclusion BSH can increase proliferation of Hela and HIEC cells irradiated by γ-ray.
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Received: 20 October 2011
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