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| Therapeutic Effect Analysis of Three Dimensional Conformal Radiotherapy Non-Small Cell Lung Cancer |
| YAO Zhi-jun, CAO Yong-zhen, ZHANG Wen-xue, LIANG Feng |
| Department of Radiation Oncology, General Hospital, Tianjin Medical University, Tianjin 300052 China |
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Abstract Objective To analysie the treatment effect of non-small cell lung cancer of three dimensional conformal radiotherapy(3D-CRT) and to study the effect of patient survival related factors. Methods Retrospective analysis was mack for 136 cases of non-small cell lung cancer, all accept 3D-CRT, through the case data collection and long-term follow-up, using the single factor and multiple factor analysis survival time and its influencing factors. Results The recent curative effects of 136 cases of patients with three dimensional conformal radiotherapy:Complete response (CR) 14.7% (20/136), partial response (PR) 60.3(82/136),stable disease (SD) 19.9% (27/136),progression disease (PD) 5.1% (7/136),total effective rate is 75% (102/136). One、two、three、five year survival rate is 79.4%、45.4%、22.1%、12.5%. Side effects:Class 1 radiated esophagitis 35 cases, Class 2 radiated esophagitis 16 cases, Class 3 and above radiated esophagitis 0 case. Class I radiated pneumonia 20 cases, Class 2 radiated pneumonia 9 cases, Class 3 radiated pneumonia 0 case. Single factor analysis shows the influence of gender, age, pathology, phase, dose, and first-phase curative effect to the survival time are of a statistical significane, Multiple factor analysis showed KPS score, phase, dose, first-phase curative effect are the survival time independent factors. Conclusion 3D-CRT for patients with non-small cell lung carcinoma is a safe, effective treatment method, Side effects are relatively low, and the patients survival time is long after radiotherapy.
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Received: 16 September 2011
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