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| Effects of Traditional ShengBaiYin on Immune and hematopoietic function of Leukopenia Animal Model in Mice |
| LIAO Ze-yun1, LI Yu-shan1, JIANG Jin-lin2, et al |
| Medical school of Hubei Institute for Nationalities, Enshi 445000 China |
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Abstract Objective To study the effects of Shengbaiyin on functions of immune system and bone marrow in mice.Methods Models of leucocytopenia induced by irradiation were prepared by 60Coγ-ray and by cyclophosphamide injection.The shengbaiyin was administrated orally.The white blood cell (WBC) counts, reticulocyte count, the number of nucleated bone marrow cells (NNBMC), T cell transformation indices (TCTI), activity of tunmor necrosis factor (TNF) and interleukin-6(IL-6) in blood of leukopenia mice on the 5th, 10th, 15st day after chymisty therapeutics were checked.Results WBC, reticulocyte count, NNBMC, TCTI be come down remarkablely, activity of TNF, IL-6 in blood were decreased obviously.These hematopoiesis indexes and the activity of TNF, IL-6 increased after oral administration of Shengbaiyin 40, 60, 80g kg.bw.Conclusion Shengbaiyin can significantly ameliorate immunological function and stimulate hematopoietic function in mice.
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Received: 08 May 2006
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