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| The study of the E838 effect on the augment of radiation treatment in mouse inoculated S180 strain |
| WANG Yue-ying1, ZHANG Liang-an1, WANG Ru-qing1, et al |
| Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192 China |
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Abstract Objective To observe E838's activity of reatraining turmor growth in mouse and discuss the relative mechanism.Methods We used three different doses of E838 to restrain turmor growth in S180 mouse in one team and the other used 137Csγ together.Results In one team, the percent of the E838(dose:low to high) restraining turmor growth is respectively 49.52%、54.81%、53.85%, in the other is respectively 52.12%、59.62%、59.62%.Not only the turmor growth of the latter team is slow but the amount of BMNC is high Conclusion E838 can obviously restrain the turmor growth in s180 mouse and has the radiation augment effect.
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Received: 27 February 2006
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