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| Study on the Anti-Radiation Effect of Soyisoflavone and Soyasaponins |
| SUN Wei-qi1,2, GUO Ying2, ZHANG Yi-quan2, et al |
| Department of Nutrition and Food hygiene, College of Public Health, Jilin University Changchun 130021 China |
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Abstract Objective To investigate the anti-γ radiation effect of soyisoflavone and soyasaponins.Methods Three batches in the experiment In every batch.clean rank of Kunming male mice were randomly divided into four groups:normal control group, radiated group, soyisoflavone group and soyasaponins group according to their weight.The mice in soyisoflavone group and soyasaponins group were fed with soyisoflavone and soyasaponins for 30 days successively, then the mice were irradiated by 60Coγ-rays in the whole body except those in the normal control group.After radiation, these two groups were fed equally as before.WBC contents, the Granulocytes and the Micronucleated polychromatic erythrocytes in bone-marrow, SOD activities and MDA contents in the blood and liver were measured.Results On the third and the fourteenth day after radiation, the number of WBC in the blood and the number of the Granulocytes in bone-marrow, the activities of SOD in the blood and liver in soyisoflavone group and soyasaponins group were significantly higher than that of radiated group (P<0.05).The number of the Micronucleated polychromatic erythrocytes in bone-marrow and MDA contents in the blood were significantly lower than that of radiated group (P<0.05).Conclusion Soyisoflavone and soyasaponins could prevent the WBC in distal blood and the Granulocytes in bone-marrow decreasing in number after radiation, restrain the production of the Micronucleated polychromatic erythrocytes, improve the antioxidant ability of radiated mice, and release the irradiation injury from γ-rays.
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Received: 15 January 2007
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