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| Effects of 9402 to the Sensibility of the Epithelia of Mouse Small Intestinal Crypts |
| LIU Xiao-qiu, WANG Rong-xian, et al |
| Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China |
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Abstract Objective To observe on the effect of 9402 to the sensibility of the epithelia of mouse small intestinal crypts.Methods Put tissue slices of the mouse small intestinal under the microscope, and then to observe the number of the regenerated mouse small intestinal crypts under different dose of sole radiation, and radiation plus drug.Results In the circumstances of different dose, it all showed no obvious difference between the sole radiation group and the group of radiation plus drug.Upon statistic adjustment, it still did not show obvious difference (P>0.05).In case of joint implementation of 9402 and 60Coγ, the sensibility ratio is 1.02.Conclusion 9402 has no obvious effect to the sensibility of normal small intestinal crypts.
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Received: 07 March 2006
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