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| Study on Radiation Protection of Hemopoietic System of Oligo-Chitosan for Mice |
| Guo Jian-ping, YANG Zhong-tian, ZHOU Chao-dong |
| China Institute for Radiation Protection, Taiyuan 030006 China |
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Abstract Objective To study the radiation protection of hemopoietic system of oligo-chitosan for mice injured by 60CO irradiation.Methods Using 60Co γ-ray irradiated mice,the influence of Oligo-chitosan on 30 d survival rate,mitotic index of marrow,colony-forming unit-spleen,index of spleen and nucleated cell count in bone marrow of the irradiated mice were observed.Results The results show that Oligo-chitosan could increase their 30 d survival rate;increase significantly MI and nucleated cell count in bone marrow at middle and high doses and CFU-S at high dose.Conclusion Oligo-chitosan could reduce the injury by radiation and protect hemopoietic system of radiated mice.
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Received: 22 April 2009
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