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| Application of low-dose CT in lung cancer screening |
| BI Jinling, SHENG Mao, DING Lu, HUANG Yong |
| Department of Oncology, Guangde Road, Hefei Second People's Hospital, Hefei 230011 China |
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Abstract Objective To explore the value of pulmonary nodules in low-dose CT and follow-up standard diagnostic CT for lung cancer screening. Methods A total of 21 subjects who have been screened for lung cancer by low-dose CT and follow-up standard diagnostic CT were randomly selected. Both CT image sets for all subjects were independently evaluated by five specialized physicians. Results There were no significant differences between low-dose CT screening and follow-up standard diagnostic CT for lung cancer screening. The concordance rate for the diagnoses of nodule disease was approximately 82% (P<0.001)for all categories. Agreement of the evaluation of all categories in the final diagnosis exceeded 96% (P<0.001). With low-dose CT, the effective dose ranged from 1.5 to 3.6 mSv, whereas in the follow-up diagnostic CT, the effective dose ranged from 8.7 to 15.2 mSv. Conclusion Low-dose CT can be effectively used as an alternativeto standard-dose CT in order to reduce the radiation dose, in the follow-up of pulmonary nodules.
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Received: 03 March 2018
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