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| Analysis of chromosome aberrations in peripheral blood lymphocytes of some radiation workers in Shandong Province |
| SONG Xueshu1, DONG Zhenqiang2, SUN Bingmei1, YU Weisong1, ZHANG Hua1, SUN Xiaowei1, CHEN Jing1, CHEN Yanxia1 |
1. Qingdao Central Hospital, Qingdao 266042 China;
2. Guangrao County Women and Children Hospital |
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Abstract Objective To understand the chromosome aberrations of peripheral blood lymphocytes of some radiation workers in Shandong Province, and provide theoretical basis for occupational health monitoring and follow-up work of radiation workers. Methods A total of 819 radiation workers were randomly selected from the institutions for occupational health examinations from 2016 to 2017, aged 22 to 59 years, including 190 industrial application groups (industrial flaw detection, nuclear power plants), and 629 medical application groups (radiation diagnosis, treatment, nuclear medicine, intervention, etc.), for the observation group; 100 people were selected as the control group. According to the "Detection and Evaluation of Peripheral Blood Lymphocyte Chromosome Aberration", chromosome aberration analysis and results were determined. SPSS 22.0 statistical software was used for analysis. The count data was expressed as a percentage, and the ratio was compared by χ2 test. The difference was statistically significant at P<0.05. Results The total chromosome aberration rate (0.11%) of the observation group was significantly higher than that of the control group (0.03%), and the difference was statistically significant. No abnormalities were found in 100 patients in the control group and other medical application groups. In the observation group, 1 case of dicentric chromosomal aberrations wasfound in 190 people from the industrial application group,and 2 cases of double centromere aberrationfound in 56 interventional medical workers, 3 abnormalities were found in the observation group. Conclusion The chromosomal aberration rate of peripheral blood lymphocytes in some radiation workers in Shandong Province was significantly higher than that of the normal population. The abnormal rate of chromosomal aberrations in the intervention group wassignificantly higher than that of other radiation workers.
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Received: 19 December 2018
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