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The study about the setup error and its effect on dose distribution in IMRT for prostate cancer patients |
GAO Xuan, LI Kexin, JU Yongjian, CAO Liyuan |
Department of Radiation Oncology, The First People's Hospital of Nantong City, Nantong 226001 China |
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Abstract Objective To Analyze the setup error and its effect on dose distribution in IMRT for prostate cancer patients.Methods 45 prostate cancer patients underwent CBCT as the first treatment and compared with the original treatment plan to get the value of bed shifting. Then the setup error were calculated though these values, and patients were divided into two groups, A (≤ 6mm) and B (> 6mm). Then the patients'differences of age, BMI, bladder and rectum volume changes in A and B were compared. Also after bed shifting, the dose parameters of target and OARS were recalculated and compared with that calculated from original treatment plan.Results 1. The bed shifting values in X, Y and Z directions of 45 patients are 0.020 ±0.407 cm, -0.031 ±0.424 cm and -0.107±0.273 cm individually. 2. The difference of BMI between A (23 patients) and B (22 patients) has statistically significant, but the difference of age, bladder and rectum volume changes have no statistically significance. 3. Compared the dose parameters between original plan and latter plan after shifting the treatment bed, the differences of PTV95, the average dose of PTV, CTV95, average dose of CTV and the bladder V60 all have statistically significance, But the differences of rectum V60 and femoral head V20 have no significant difference.Conclusion In prostate cancer patients IMRT,the setup error must be care about, it may be related to the patient's BMI, but has limited/no relationships with the ageand bladder rectal volume changes in this study, and it must be corrected by shifting treatment bed, otherwise it will cause the dose distribution error in the target area and OARs.
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Received: 05 December 2017
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