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| Matched case-control study on the influencing factors of lymphocyte micronucleus rate abnormality in radiation workers |
| WANG Chang, LI Jinrong, MO Sufang, ZHANG Jingbo, TAN Hanyun, LI Xiaotong |
| Guangzhou Center for Disease Control and Prevention, Guangzhou 510440 China |
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Abstract Objective To understand and discuss the incidence and influencing factors of the lymphocyte micronucleus abnormality in the radiation workers in Guangzhou.Methods Using 1:1 matched case-control study. Case group:from January 1, 2014 to December 31, 2014, the lymphocyte micronucleus rate is greater than or equal to 6‰ in the 1050 radiation workers who took occupational health examinations in a center, with a total of 24 cases. Control group:24 cases of radiation workers who had been examined at the same center and were in the same work unit, gender, age difference ±5 years, and lymphocyte micronucleus rate were normal. According to the occupational health examination form for radiation workers to collect the general baseline, the ionizing radiation exposure, the contact of confounding factors and the physical examination project indicators of research object. And single factor and multifactor conditional logistic regression analysis was respectively used to analyze the influencing factors of the abnormal lymphocyte micronucleus rate.Results The incidence of the lymphocyte micronucleus abnormality of radiation workers in Guangzhou was 2.29﹪. Smoking or passive smoking was the only statistically significant variable (OR=3.667).Conclusion The abnormal condition of lymphocyte micronucleus of the radiation workers in Guangzhou is normal, Smoking or passive smoking is the possible risk factor for the exceeded lymphocyte micronucleus rate.
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Received: 09 January 2018
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