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| Study on cellular survival adaptive response induced by low dose irradiation of 153Sm |
| Zhu Shoupeng, Xiao Dong |
| Suzhou Medical College, Suzhou 215007 |
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Abstract The present study engages in determining whether low dose irradiation of 153Sm could cut down the responsiveness of cellular survival to subsequent high dose exposure of 153Sm so as to make an inquiry into approach the protective action of adaptive response by second irradiation of 153Sm. Experimental results indicate that for inductive low dose of radionuclide 153Sm 3.7 kBq/ml irradiated beforehand to cells has obvious resistent effect in succession after high dose irradiation of 153Sm 3.7×102kBq/ml was observed. Cells exposed to low dose irradiation of 153Sm become adapted and therefore the subsequent cellular survival rate induced by high dose of 153Sm is sufficiently higher than high dose of 153Sm merely. It is evident that cellular survival adaptive response could be induced by pure low dose irradiation of 153Sm only.
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Received: 18 September 1998
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