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| Experimental Observation of G Banding Verifying X-ray Workers' Chromosome Translocation Detected by FISH |
| SUN Yuan-ming, LI Jin, WANG Qin, et al |
| Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China |
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Abstract Objective FISH is the most effective way of detecting chromosome aberration and many factors affect its accuracy.G-banding is used to verify the results of early X-ray workers' chromosome translocation examined by FISH.Methods The chromosome translocations of early X-ray workers have been analysed by FISH (fluorescence in situ hybridization) and G-banding,yields of translocation treated with statistics.Results The chromosome aberrations frequencies by tow methods are closely related.Conclusion FISH is a feasible way to analyse chromosome aberrations of X-ray workers and reconstruct dose.
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Received: 14 May 2001
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