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| Influence of Tremella Fuciformis Berk Spores Polysaccharide A-BTF to Chromosome Aberration and Micronucleus Rate of Marrow Cells in Mice Irradiated by 137Cs γ-ray |
| YAN Yu-jun, XU Wen-qing, SHEN Xiu, WANG De-zhi, ZHAO Yun-ting, ZHOU Ze-wei |
| Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192 China |
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Abstract Objective To study the influence of a homogeneity polysaccharide A-BTF extracted from tremella fuciformis berk spores to chromosome aberration in cells of bone marrow of mice and micronucleus rate of polychromatic erythrocyte induced by 137Cs γ-ray irradiation. Mehtods Extracted polysaccharide of tremella fuciformis berk spores was administered by intra-abdominal injection at 24 hours before irradiation, and control mice were given physiological saline. The mice were irradiated by 137Cs γ-ray, then observed on chromosome aberration of bone marrow cells and micronucleus rate of polychromatic erythrocyte. Results The Results show that occurrence of chromosome aberration and micronucleus rate was obviously lower in mice administered prevention with polysaccharide than that of simply irradiated control mice, and with quite significant differece (P < 0.01). Conclusion It manifests that the homogeneity polysaccharide from tremella fuciformis berk spores is of marked protective effects for damages of bone marrow cells by irradiation.
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Received: 29 October 2013
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