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| The Effect of Electromagnetic Irradiation on PKC Translocation and Activation |
| DENG Zhao-hui1, WANG Deng-gao2, ZHANG Lei1, et al |
| Third Military Medical University, Chongqing, 400038, China |
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Abstract Objective To study the effect of electromagnetic irradiation on PKC translocation and activation.Methods After exposure to 5 W/cm2 microwave, the change of PKC kinase activity in rat hippocampus was detected by Takai method, AMPA receptor phosphorylation level was determined by Western-blotmethod.Results 5 W/cm2 microwave irradiation increased PKC kinase activity after exposure 3~5d and this effect continued for 15d, and the irradiation have no obvious effect on AMPA receptor phosphrylation in rat hippocampus.Conclusion The results showed that PKC-AMPA pathway may not be involved in the central nervous system injury induced by 5 W/cm2 microwave irradiation.
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Received: 18 November 2005
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