|
|
|
| The protective effect of micronutrient intervention on peroxidation damage induced by microwave irradiation on rat hippocampus |
| GONG Qian-feng1, YANG Xue-sen2, DENG Zhao-hui2, et al |
| Nutrition Department, The Southwest Hospital No.3 Military Medical University, Chongqing 400038 China |
|
|
|
|
Abstract Objective To observe the peroxidation of rat hippocampus after acute or chronic microwave irradiation and research the protective effects of micronutrient intervention.Methods by microwave at 15 W/cm2 for 20min everyday for 8 weeks continuously.The peroxidation damage of hippocampus by microwave and the protective effect of micronutrient intervention were detected by measuring SOD、MDA、GSH-PX and ROS.Results The acute and chronic microwave irradiation could induce the down-regulating SOD activity, GSH-Px activity, ROS inhibition (P<0.05) and up-regulate the content of MDA obviously (P<0.05).After micronutrient intervention, SOD and GSH-Px activity increased (P<0.05), the content of MDA reduced (P<0.05), ROS inhibition resumed (P<0.05).Conclusion The acute and chronic microwave irradiation can induce the oxidative of rat hippocampus.Micronutrient intervention has protective effect on the peroxidation damage induced by microwave irradiation.
|
|
Received: 26 May 2008
|
|
|
|
|
|
|
|
|
