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| The Preparation and Characterization of CTS-EDTA and the Study of its Chelating Sr2+ in Vitro |
| ZHANG Liu-zhen, XU Yu-jie, WANG Chang, et al |
| School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123 China |
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Abstract Objective To obtain chitosan(CTS)-ehylene diamine tetraacetic acid(EDTA) compound(CTS-EDTA compound),and compare the chelating ability to Sr2+ of CTS and CTS-EDTA.Methods To synthesize CTS-EDTA compound by N-acylation reaction,and use atomic absorption spectrometry to measure the Sr2+ concentration changes in the SrCl2 solution with CTS and CTS-EDTA respectively.Results FTIR and 1H-NMR spectrum showed that CTS-EDTA compound was made successfully,and CTS-EDTA's chelating efficiency to Sr2+ was over 80% in 10min,but CTS was almost the same as Control.Conclusion CTS-EDTA's chelating ability to Sr2+ was obiviously better than CTS.
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Received: 22 October 2008
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