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| Meta Analysis of the Effect of Low Dose Ionizing Radiation on Peripheral Blood Cells of Radiation Workers |
| ZHANG Xin, ZHAO Yong-cheng |
| Tianjin Key Laboratoty of Radiation Medicine and Molecular Nuckar Medicine, Institute of Radiation Medicine, Chinse Academy of Medical Sicience & Reking Union Medical College, Tianjin 300192 China |
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Abstract Objective To assess the effect of low dose ionizing radiation on the peripheral blood cells of radiation workers in our country by using Meta analysis method.Methods According to the predefined inclusion and exclusion criteria,the relevant literatures were searched,the number of workers exposed to radiation,the abnormal number of white blood cell,hemoglobin,platelet in Peripheral blood and abnormal rate were basic data,the heterogeneity of data was tested,the OR was as effect size,and the fixed effects model or random effects model was used to meta analysis.Results In meta analysis of Low dose ionizing radiation for radiation workers in white blood cells,the combined OR was 1.81,95% CI was (1.23,2.65).The risk of abnormal white blood cells of radiation workers was higher than that of the non radiation workers.In meta analysis of Low dose ionizing radiation for radiation workers in hemoglobin,the combined OR was 0.83,95% CI was(0.63,1.08).There was no statistical difference between the radiation group and the control group In meta analysis of Low dose ionizing radiation for radiation workers in platelet,the combined OR was 1.30,95% CI was (0.89,1.90).There was no statistical difference between the radiation group and the control group.Conclusion Long term exposure to low dose ionizing radiation environment will significantly increase the radiation workers abnormal WBC rate,but it has no significant effect on hemoglobin and platelet.
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Received: 10 April 2016
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