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| Study on Free Radical and Antioxidant Ecological Network System Theory Model and Its Application |
| SUN Hua-bin, YU Xiu-xin, ZHAO Yong |
| Center for Disease Control and Prevention of Jinan Military Command, Jinan 250014 China |
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Abstract Objective To put forward and establish a unified theory of free radicals and antioxidants bilolgical effect model to quantitatively describe and explain biphase of diversity of the bilolgical effects of free radicals and antioxidant, and apply to the medical protection in NCB damage. Methods Summarize the latest achievements in free radicals and antioxidants in biomedical, put forward 10 basic principles to establish the unified theory of free radicals and antioxidants eclolgical network system model. Results Free radicals and antioxidants ecological network system theory model is proposed and 3 model equations are established, they can quantitatively describe and explain the biphase or diversity biological effects of free radicals and antioxidants, and put forward the unified stress damage mechanism and protective measures induced by NCB damage. Conclusion Free radicals and antioxidants ecological network system theory and the model can quantitativerly describe and explain the biploar or diversity biological effects of free radicals and antioxidants, can also be applied to other generalized stress stimulus:physical factors, chemical factors and bilolgical factors, psychological, drugs, poisons, etc. This is a generalized ecological network stystem theory model for oxidative stress and redox stress.
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Received: 17 August 2013
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