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Dosimetric study on intensity-modulated radiotherapy with dissimilar position on peripheral normal tissues and organs of cervical cancer |
MIAO Hui1, SHI Linxin1, BAI Haisheng2, SHAO Weixian1, YUAN Cheng1, LIU Yazhou1, SUN Suping1, CHEN Honglin1, LUO Jujian1, HUI Hua1, ZHANG Wen1 |
1. Xuzhou Cancer Hospital, Xuzhou 221000 China; 2. Xinyi Hospital of Traditional Chinese Medicine |
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Abstract Objective To analyze the difference of irradiation dose of organs at risk (OAR) between supine position and prone position on intensity-modulated radiotherapy (IMRT) for cervical cancer. Methods Fourteen patients scheduled to receive postoperative radiotherapy for cervical cancer were scanned with supine position and prone position by CT. The CT images were transported to TPS, then the IMRT plans were designed respectively. HI and CI of the planning target volume (PTV) and irradiation dose of OAR were evaluated. To appraise the difference between the techniques, the paired t-test was applied. Results Both groups showed excellent dose coverage to the clinical target volume. There was no significant difference in CI and HI of PTV between the two groups (P=0.211, 0.190). Compared with supine position, patients with prone position had significantly lower V40 and V50 of the small bowel (P<0.05). The V40 of colon and V50 of pelvis were also lower in Prone-IMRT group (P<0.05). The irradiation dose of rectum, bladder, femur head, spine cord and sigmoid were no obviously differences at dissimilar position (P>0.05). Conclusion The application of prone position in IMRT for cervical cancer patients can reduce the dose of small intestine and other organs, thus reducing the occurrence of adverse reactions, and has clinical application value.
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Received: 20 February 2018
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