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| Correlation between ADC value of MR diffusion-weighted imaging and grading in colorectal adenocarcinoma |
| XU Huihui, FENG Changming, HUO Yingjie, HE yanan, LI peixiu |
| The Central Hospital of CNPC, Langfang 065000 China |
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Abstract Objective To investigate the correlation between apparent diffusion coefficient (ADC)value of MR diffusion weighted imaging (DWI)and grading in colorectal adenocarcinoma.Methods The data of 36 patients with colorectal neoplasms confirmed by pathology were retrospectively analyzed. MRI、DWI and enhanced examination were performed preoperatively. ADC values were calculated in each group to analyze the correlation with the grading colorectal adenocarcinoma by pearson correlation analysis.Results The mean ADC value were(0.734±0.070)×10-3 mm2/s in the poorly differentiated group(2 cases), (0.966±0.157)×10-3 mm2/s in the moderately differentiated group (10 cases).ADC value and grading colorectal adenocarcinoma were strong correlated (r=0.692,P=0.000). The three groups of high and low score ADC values were not statistically significant, The difference between the moderately differentiated group and the well-differentiated group (P=0.000) was statistically significant.Conclusion The ADC values of colorectal tubular carcinomas with different degrees of differentiation decrease with the degree of differentiation of the tumors. The two are correlated and provide a strong basis for evaluating the differentiation of colorectal tubular adenocarcinoma preoperatively. DWI and ADC measurement can evaluate the grade of malignancy and prognosis of colorectal tumor to some extent.
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Received: 20 October 2017
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