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| Comparative study of dose distributions calculated by dual optimization modes of Monaco system by volumetric modulated arc therapy of nasopharyngeal carcinoma |
| HE Ruixin1, YUAN Wei1, XU Chao1, ZHANG Yuemei1, HAN Yangpeng1, TANG Fengwen1, GONG Tuotuo1, WANG Hu???????it???????ao2 |
1. The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an 710061 China;
2. Anyang Tumor Hospital, Anyang 455001 China |
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Abstract Objective To compare the dosimetric differences in volumetric modulated arc therapy (VMAT) of Monaco planning system for nasopharyngeal carcinoma between Pareto and Constrained optimization in order to provide a reference for future mode selection.Methods Select 20 patients with nasopharyngeal carcinoma whom were calculated by Pareto and Constrained modes in the same CT image. Prescription dose of target PGTV, PTV1 and PTV2 was 70.29、60.39 and 54.45 Gy with 33 fractions, 5 times a week. The differences in target dose, organs at-risk dose, monitor units and segments were compared in the condition of 95% of the target volume reached the prescribed dose.Results Compared with Pareto group, Constrained group achieved a better HI and CI. CI of PGTV and PTV1 signed statistical differences (P < 0.05). Dose of OARs in Constrained group were all lower than those in Pareto group except Optical-l and lens-l. The differences of spinal cord prv dose and V30 of Parotid-r between two groups was significant (P < 0.05) while the differences of monitor units and segments between two groups was not significant (P > 0.05).Conclusion The length of middle turbinate is negatively correlated with the occurrence and severity of CMS. There is no significant correlation between the degree of curling and the occurrence of CMS, but patients with lower degree of curling of middle turbinate may have more serious CMS.
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Received: 23 January 2021
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[1] 梁锌, 杨剑, 高婷, 等. 中国鼻咽癌流行概况[J]. 中国肿瘤,2016,25(11):835-840. DOI: 10.11735/j.issn.1004-0242.2016.11.A00118,19(1):
Liang X, Yang J, Gao T, et al. Nasopharynx cancer epidemiology in China[J]. China Cancer, 2016, 25(11): 835-840. DOI: 10.11735/j.issn.1004-0242.2016.11.A00118,19(1):
[2] Taggar AS, Graham D, Kurien E, et al. Volumetric-modulated arc therapy versus intensity-modulated radiotherapy for large volume retroperitoneal sarcomas: a comparative analysis of dosimetric and treatment delivery parameters[J]. J Appl Clin Med Phys, 2018, 19(1): 276-281. DOI: 10.1002/acm2.12230
[3] Della Gala G, Dirkx MLP, Hoekstra N, et al. Fully automated VMAT treatment planning for advanced-stage NSCLC patients[J]. Et Al, 2017, 193(5): 402-409. DOI: 10.1007/s00066-017-1121-1
[4] 徐洋洋, 邓磊, 杨亚新, 等. 放射治疗外照射的蒙特卡罗计算[J]. 中国辐射卫生,2016,25(1):15-17. DOI: 10.13491/j.cnki.issn.1004-714x.2016.01.005
Xu YY, Deng L, Yang YX, et al. Radiotherapy Monte Carlo calculation of dose rate[J]. Chin J Radiol Health, 2016, 25(1): 15-17. DOI: 10.13491/j.cnki.issn.1004-714x.2016.01.005
[5] 邹剑明, 许志强, 耿继武, 等. 基于蒙特卡罗方法的质子治疗室屏蔽防护探讨[J]. 中国辐射卫生,2019,28(4):443-446. DOI: 10.13491/j.issn.1004-714x.2019.04.026
Zou JM, Xu ZQ, Geng JW, et al. Radiation shielding design of proton therapy treatment room based on the Monte Carlo method[J]. Chin J Radiol Health, 2019, 28(4): 443-446. DOI: 10.13491/j.issn.1004-714x.2019.04.026
[6] Hodapp N. The ICRU Report 83: prescribing, recording and reporting photon-beam intensity-modulated radiation therapy (IMRT)[J]. Et Al, 2012, 188(1): 97-99. DOI: 10.1007/s00066-011-0015-x
[7] ICRU report 62: Prescribing, recording, and reporting photon beam therapy(supplement to ICRU Report 50)[S]. Bethesda, MD: International Commission on Radiation Units and Measurements, 1999.
[8] 程婷婷, 张彦秋, 张子健, 等. 晚期鼻咽癌螺旋断层调强放疗与容积旋转调强放疗剂量学比较[J]. 中国医学物理学杂志,2018,35(9):1005-1011. DOI: 10.3969/j.issn.1005-202X.2018.09.003
Cheng TT, Zhang YQ, Zhang ZJ, et al. Dosimetric comparison of helical tomotherapy and volumetric modulated arc therapy for latestage nasopharyngeal carcinoma[J]. Chin J Med Phys, 2018, 35(9): 1005-1011. DOI: 10.3969/j.issn.1005-202X.2018.09.003
[9] 张思娜, 陈善义. 鼻咽癌放射治疗[J]. 世界最新医学信息文摘,2019,19(60):36-37. DOI: 10.19613/j.cnki.1671-3141.2019.60.016
Zhang SN, Chen SY. Review of Radiotherapy of Nasopharyngeal Carcinoma[J]. World Latest Medicne Information, 2019, 19(60): 36-37. DOI: 10.19613/j.cnki.1671-3141.2019.60.016
[10] 张惠玲, 李鑫, 吴小良, 等. 分段弧和全弧旋转容积调强放疗治疗胸中段食管癌的剂量学比较[J]. 中国辐射卫生,2020,29(1):81-84. DOI: 10.13491/j.issn.1004-714X.2020.01.019
Zhang HL, Li X, Wu XL, et al. Dosimetry comparison of partial-arc and full-arc volumetric modulated arc therapy for middle esophageal cancer[J]. Chin J Radiol Health, 2020, 29(1): 81-84. DOI: 10.13491/j.issn.1004-714X.2020.01.019
[11] 洪楷彬, 张瑜, 柏朋刚, 等. 控制点数量设定对Monaco5.11计划系统制定鼻咽癌单弧容积旋转调强放射治疗计划的剂量学影响[J]. 中国医学装备,2018,15(1):18-21. DOI: 10.3969/J.ISSN.1672-8270.2018.01.006
Hong KB, Zhang Y, Bai PG, et al. Influences of the setting of control point number on the formulation of Monaco5.11 plan system for the dosimetry of single volumetric modulated arc therapy plan of nasopharyngeal carcinoma[J]. China Med Equip, 2018, 15(1): 18-21. DOI: 10.3969/J.ISSN.1672-8270.2018.01.006
[12] 曹洋森, 于春山, 孙永健, 等. Monaco两种优化模式在前列腺癌容积旋转调强中的剂量学比较[J]. 中国医学物理学杂志,2016,33(11):1126-1129, 1143. DOI: 10.3969/j.issn.1005-202X.2016.11.009
Cao YS, Yu CS, Sun YJ, et al. Comparison of dose distribution calculated by two optimization models of Monaco system in volumetric modulated arc therapy for prostate cancer[J]. Chin J Med Phys, 2016, 33(11): 1126-1129, 1143. DOI: 10.3969/j.issn.1005-202X.2016.11.009
[13] 谢红亮, 胡灿, 曹洋森, 等. 基于Monaco的食管癌容积旋转调强计划中两种优化模式的剂量学比较[J]. 中国医学物理学杂志,2018,35(7):745-748. DOI: 10.3969/j.issn.1005-202X.2018.07.001
Xie HL, Hu C, Cao YS, et al. Comparison of dose distributions calculated by two optimization methods of Monaco system used in volumetric modulated arc therapy of esophageal cancer[J]. Chin J Med Phys, 2018, 35(7): 745-748. DOI: 10.3969/j.issn.1005-202X.2018.07.001
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