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| Analysis of individual annual efficient dose and micronucleus results in peripheral blood lymphocytes of 921 radiation workers |
| LI Jie, HAN Lin, WANG Ping, TIAN Chongbin, LV Yumin |
| Henan Institute of Occupational Medicine, Zhengzhou 450052 China |
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Abstract Objective To explore the relationship between individual exposure dose and micro-nucleus of peripheral blood lymphocytes and provide basis for radiation protection of radiation workers. Method 921 radiation workers were included in this study and were divided into five groups according the type of work[including radiodiagnosis(n=481), radiotherapy(n=153),nuclear medicine(n=83), interventional radiology(n=90)and Industrial flaw detection(n=114).]And micro-nucleus test was used by whole blood of tiny culture method. Results According to the statistical analysis, there was significant difference in the annual average effective dose among the five groups(F=33.809,P<0.05),and it was significant higher in nuclear medicine group and interventional radiology group than that in radiodiagnosis group,radiotherapy group and Industrial flaw detection group(P<0.05);Meanwhile,the micronucleus rate of the interventional radiology group was significantly higher than that of radiodiagnosis group and radiotherapy group(P<0.05).But there was no significant dose-effect relationship between micronucleus rate and individual annual effective dose (P>0.05).Comparison of microuncleus rates among different physical examination categories showed statistically significant differences between pre-job and on-job groups(χ2=168.526,P<0.05).With the increase of age,the micronucleus rate in on-job group tended to rise roughly(P<0.05). Conclusion The genetic damage induced by low dose ionizing radiation still exists in radiation workers. Effective protective measures of interventional and nuclear medical workers should be strengthened to reduce radiation damage.
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Received: 11 April 2019
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