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Adaptive response of TfR expression induced by low dose radiation in splenocytes of mice |
Luo Can, et al |
MH Radiobiology Research Unit of Norman Bethune Midical University, Changchun 130021 |
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Abstract Using direct immunoflurescence and flow cytometric analysis, Transferrin recepor (TfR) expression and adaprtive response were examined in lymphocytes in mouse spleens 24 hours after whole body irradiation (WBI) with low dose X-rays.The results showed that WBI with 75 mGy X-rays could enhance TfR expression in lymphocytes in mouse spleens, and could reduce the inhibition to TfR expression by 2Gy irradiation after given 75 mGy irradiation and induce adaptive response of TfR expression.It is demonstrated that TfRs may play a role in immune adaptive response induced by low dose radiation.
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Received: 26 January 1999
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