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| The Analysis of Distribution of the Chromosome Aberration Breakpoints from Medical Diagnostic X-ray Workers |
| WANG Qin, LI Jin, TANG Wei-sheng, et al |
| Institute of Radiation Medicine, Chinese Academy of Medical Sciences and peking Union Medical College, Tianjin 300192, China |
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Abstract Objective To analyze the distribution of the chromosome aberration breakpoints from medical diagnostic X-ray workers.Methods The breakpoints of lymphocyte chromosomes are analyzed using G-banding.Results There are 146 breakpoints among 3 545 metaphase in 37 cases of X-ray workers.There are statistically significant differences between observed values and expected values (χ2=42.82, df=23, P < 0.01).There are 17 breakpoints among 908 metaphase in 10 controls.There are not statistically significant differences between observed values and expected values (P >0.05).Conclusion The chromosome aberration breakpoints of medical diagnostic X-ray workers are non-random.The observed values of breakpoint numbers are higher than those of the expected values in 7 and 14 chromosomes (P < 0.05)
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Received: 29 July 2002
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