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| Analysis on CB Micronucleus in Peripheral Blood Lymphocytes of Workers in A Gold Mine |
| MA Ya, CHEN Ying-min, HOU Dian-jun, et al |
| Institute of Radiation Medicine, Shandong Academy of Medical Sciences, Jinan 250062 China |
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Abstract Objective To investigate the peripheral blood lymphocyte micronucleus rate changes of the underground gold mine workers.Methods Cytokinesis-block micronucleus test analysis of micronucleus rate changes in the peripheral blood lymphocyte was made in the staff of one gold mine in our province.Results The peripheral blood lymphocyte micronucleus cell rate was 10.8‰ in 56 underground workers,micronucleus rate of 11.6 ‰,significantly higher than that of the normal control group (8.7‰,9‰) P<0.05.There are signifieant differences between the mine workers of various work age groups and the control group in statistical analysis (P<0.05).Micro-nuclear detection rate in workers of 6~10 years and over 20 years of work was significantly higher those under 5 years.There is a marked statistical significance (P<0.05),but there is no statisticall significance among other work age groups (P>0.05).Conclusion The gold mine employees in the DNA genetic material has been subject to varying degrees of damage.To minimize the occupational hazards,it is necessary to strengthen the prevention and control measures.
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Received: 16 August 2009
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