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Application of cross-modality fusion images of 18F-FDG SPECT and GE 64 row CT in diagnosis of colorectal neoplasms |
ZHANG Yongqiang1,2, WANG Yunlu2,3, LIANG Yan2,3, LI Zhanzhan2, ZHAO Jie3, HE Zilong1, CHEN Weiguo1 |
1. Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515 China; 2. Department of CT, Sanmenxia Central Hospital; 3. Department of Nuclear Medicine, Sanmenxia Central Hospital |
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Abstract Objective To explore the advantages of cross-modality fusion images of 18F-fluorodeoxyglucose single photon emission computed tomography(18F-FDG SPECT/CT)and GE 64 row CT in diagnosis and TNM staging of colorectal neoplasms by comparing the images quality before and after fusion of both machines.Methods Thirty-six patients of colorectal neoplasms confirmed by pathology were examined by 18F-FDG SPECT/CT and hetero machine 64 row CT. The images were transferred to the post processing workstation, and 18F-FDG SPECT images were completed and fused with low energy CT and heterogeneous 64 row CT images by the same machine. 65 lesions from 36 patients, including 36 primary,19 metastatic lymph node and 10 distant metastasis were divided into 3 groups. The images processed by co-modality fusion and cross-modality fusion were scored respectively on clarity of mass boundary, clarity with adjacent organs and image artifacts. Wilcoxon test was used to compare the quality score of co-modality fusion with those of cross-modality fusion images.Results Score of cross-modality fusion images was higher than those of co-modality fusion images, which was statistically significant(z=-5.303 and -3.858 and -2.844,P<0.01).Conclusion Cross-modality fusion images of colorectal primary tumors, lymph nodes and distant metastasis are better than co-modality fusion images. Cross-modality fusion is worthy to be popularized in clinical practice.
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Received: 16 December 2017
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