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| Observation for Biological Distribution of 99mTc-Gelatin in Mice |
| LI Ri, WANG Yan, DU Li-qing, XU Chang, TAN Gui-guo, LIU Qiang |
| Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192 China |
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Abstract Objective To explore the possibility of 99mTc-gelatin acting as imaging reagent for glomerular filtration. Methods 99mTc-gelatin was prepared by using 99Mo-99mTc generator. Rate of Radioactive uptake and radiocounting of 99mTc-gelatin were detected in heart, liver, lung, spleen, kidney and stomach of mice. Results High uptake rate and long holding period of 99mTc-gelatin were discovered in kidney, but the removal in blood was very fast. Conclusion 99mTc-gelatin was hopeful to be a kind of imaging reagent of glomerular filtration.
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Received: 09 July 2013
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