|
|
Effect of respiratory movement on the dose distribution in the TOMO therapy target area |
CHENG Xianyong1, LI Peng2, SONG Gang3, LU Feng3 |
1. Shandong Academy of Occupational Health and Occupational Medicine, Jinan 250062 China; 2. Jining Center for Disease Control and Prevention, Jining 272008 China; 3. Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062 China |
|
|
Abstract Objective To explore the effect of respiratory movement on the dose distribution in the TOMO therapy target area. Methods The motion phantom was used to simulate human respiratory movement. The SNC patient analysis software was used to compare the films of the study group with those of the control group, and the effect of respiratory movement on the dose distribution in the TOMO target area was evaluated by the “pass rate” index. Results Visual observation showed that the distribution of film gray in the head-foot direction (i.e., direction of movement) was significantly different with or without respiratory movement. Film analysis showed that the maximum deviation between the width of the target wrapping curve and the treatment plan value was about 2.4 mm at no respiratory movement and about 27.2 mm at respiratory movement; the penumbra width of the target area was 31 mm (head direction) and 28.5 mm (foot direction) at no respiratory movement and 39.7 mm (head direction) and 37 mm (foot direction) at respiratory movement; the “pass rate” of target dose distribution was only 12.3%. Conclusion Respiratory movement has a great impact on the dose distribution in the TOMO target area in the direction of movement. When making clinical treatment plan, the impact of respiratory movement on the dose distribution in the TOMO target area can not be ignored.
|
Received: 15 March 2022
|
|
|
|
|
[1] Wijenayake U, Park SY. Real-time external respiratory motion measuring technique using an RGB-D camera and principal component analysis[J]. Sensors, 2017, 17(8): 1840. DOI: 10.3390/s17081840 [2] 解佳奇, 蒋俊, 任伟, 等. 非小细胞肺癌调强放疗与螺旋断层放疗剂量学的比较研究[J]. 实用癌症杂志,2017,32(3):479-483. DOI: 10.3969/j.issn.1001-5930.2017.03.039 Xie JQ, Jiang J, Ren W, et al. Dosimetric comparison between intensity-modulated radiotherapy and helical tomotherapy for non-small cell lung cancer[J]. Pract J Cancer, 2017, 32(3): 479-483. DOI: 10.3969/j.issn.1001-5930.2017.03.039 [3] 陈明, 李建彬, 邓小武, 等. 中国放射治疗相关的器官运动管理指南[J]. 中国肿瘤,2021,30(10):726-733. DOI: 10.11735/j.issn.1004-0242.2021.10.A002 Chen M, Li JB, Deng XW, et al. China guideline for the management of organ motion related to radiotherapy[J]. China Cancer, 2021, 30(10): 726-733. DOI: 10.11735/j.issn.1004-0242.2021.10.A002 [4] Liu YC, Gu MY, Cheng Y. An excerpt of radiation therapy for pancreatic cancer: Executive summary of an ASTRO clinical practice guideline (2019)[J]. J Clin Hepatol, 2020, 36(1): 50-52. DOI: 10.3969/j.issn.1001-5256.2020.01.010 [5] Langen KM, Jones DT. Organ motion and its management[J]. Int J Radiat Oncol Biol Phys, 2001, 50(1): 265-278. DOI: 10.1016/S0360-3016(01)01453-5 [6] Clifford MA, Banovac F, Levy E, et al. Assessment of hepatic motion secondary to respiration for computer assisted interventions[J]. Comput Aided Surg, 2002, 7(5): 291-299. DOI: 10.3109/10929080209146038 [7] Seppenwoolde Y, Shirato H, Kitamura K, et al. Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy[J]. Int J Radiat Oncol Biol Phys, 2002, 53(4): 822-834. DOI: 10.1016/S0360-3016(02)02803-1 [8] 肖锋, 谭丽娜, 孙晓欢, 等. 呼吸运动对肺癌动态调强放疗剂量分布的影响[J]. 现代肿瘤医学,2012,20(3):608-611. DOI: 10.3969/j.issn.1672-4992.2012.03.53 Xiao F, Tan LN, Sun XH, et al. Influence of respiratory motion on the dose distribution in dynamic intensity-modulated radiotherapy for lung cancer[J]. Mod Oncol, 2012, 20(3): 608-611. DOI: 10.3969/j.issn.1672-4992.2012.03.53 [9] 张晋建, 黎静, 文婷, 等. Arc CHECK在乳腺癌螺旋断层放疗计划剂量验证中的应用[J]. 中国医学物理学杂志,2015,32(2):244-247. DOI: 10.3969/j.issn.1005-202X.2015.02.021 Zhang JJ, Li J, Wen T, et al. Irradiation dose verification by arc check on breast therapy cancer tomotherapy[J]. Chin J Med Phys, 2015, 32(2): 244-247. DOI: 10.3969/j.issn.1005-202X.2015.02.021 [10] 蔡汉飞, 方美芳, 徐露, 等. Gafchromic EBT3胶片在螺旋断层放射治疗计划验证中的应用[J]. 中国医学物理学杂志,2018,35(11):1257-1260. DOI: 10.3969/j.issn.1005-202X.2018.011.004 Cai HF, Fang MF, Xu L, et al. Application of Gafchromic EBT3 film in the verification of TomoTherapy plan[J]. Chin J Med Phys, 2018, 35(11): 1257-1260. DOI: 10.3969/j.issn.1005-202X.2018.011.004
|
|
|
|