Effects of occupational radiation exposure on peripheral blood lymphocyte count and cell cycle in logging workers
LI Weiguo1,2, GAO Gang1, PAN Yan1, LI Hailiang2, RUAN Jianlei1, PIAO Chunnan1, FU Jinghong2, LIU Jianxiang1
1. Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Protection, Beijing 100088 China; 2. School of Preventive Medicine (Institute of Radiation Medicine), Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250117 China
李卫国, 高刚, 潘艳, 李海亮, 阮健磊, 朴春南, 傅惊虹, 刘建香. 职业照射对测井工人外周血淋巴细胞数量和细胞周期的影响[J]. 中国辐射卫生, 2024, 33(1): 28-32,39.
LI Weiguo, GAO Gang, PAN Yan, LI Hailiang, RUAN Jianlei, PIAO Chunnan, FU Jinghong, LIU Jianxiang. Effects of occupational radiation exposure on peripheral blood lymphocyte count and cell cycle in logging workers. Chinese Journal of Radiological Health, 2024, 33(1): 28-32,39.
[1] Wang Q, Lee Y, Pujol-Canadell M, et al. Cytogenetic damage of human lymphocytes in humanized mice exposed to neutrons and X rays 24 h after exposure[J]. Cytogenet Genome Res, 2021, 161(6/7): 352-361. DOI: 10.1159/000516529 [2] Holden S, Perez R, Hall R, et al. Effects of acute and chronic exposure to a mixed field of neutrons and photons and single or fractionated simulated galactic cosmic ray exposure on behavioral and cognitive performance in mice[J]. Radiat Res, 2021, 196(1): 31-39. DOI: 10.1667/RADE-20-00228.1 [3] Little MP. Evidence for dose and dose rate effects in human and animal radiation studies[J]. Ann ICRP, 2018, 47(3/4): 97-112. DOI: 10.1177/0146645318756235 [4] Wang Y, Bannister LA, Sebastian S, et al. Low-dose radiobiology program at Canadian nuclear laboratories: past, present, and future[J]. Int J Radiat Biol, 2019, 95(10): 1361-1371. DOI: 10.1080/09553002.2018.1562252 [5] Moriyama H, Daino K, Imaoka T, et al. Neutron-induced rat mammary carcinomas are mainly of luminal subtype and have multiple copy number aberrations[J]. Anticancer Res, 2019, 39(3): 1135-1142. DOI: 10.21873/anticanres.13222 [6] Bosch De Basea Gomez M, Thierry-Chef I, Harbron R, et al. Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults[J]. Nat Med, 2023, 29(12): 3111-3119. DOI: 10.1038/s41591-023-02620-0 [7] Liu W, Haley BM, Kwasny MJ, et al. The effects of radiation and dose-fractionation on cancer and non-tumor disease development[J]. Int J Environ Res Public Health, 2012, 9(12): 4688-4703. DOI: 10.3390/ijerph9124688 [8] Metz-Flamant C, Samson E, Caër-Lorho S, et al. Solid cancer mortality associated with chronic external radiation exposure at the French atomic energy commission and nuclear fuel company[J]. Radiat Res, 2011, 176(1): 115-127. DOI: 10.1667/RR2528.1 [9] Foucault A, Ancelet S, Dreuil S, et al. Childhood cancer risks estimates following CT scans: an update of the French CT cohort study[J]. Eur Radiol, 2022, 32(8): 5491-5498. DOI: 10.1007/s00330-022-08602-z [10] Pearce MS, Salotti JA, Little MP, et al. Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study[J]. Lancet, 2012, 380(9840): 499-505. DOI: 10.1016/S0140-6736(12)60815-0 [11] 刘树铮, 苏旭, 李修义, 等. 医学放射生物学[M]. 3版. 北京: 原子能出版社, 2006: 305. Liu SZ, Su X, Li XY, et al. Medical radiobiology[M]. 3rd Ed. Beijing: China Atomic Energy Press, 2006: 305. [12] Fujikawa K, Hasegawa Y, Matsuzawa S, et al. Dose and dose-rate effects of X rays and fission neutrons on lymphocyte apoptosis in p53( + / + ) and p53( - / - ) mice[J]. J Radiat Res, 2000, 41(2): 113-127. DOI: 10.1269/jrr.41.113 [13] Bozhenko VK, Ivanov AV, Kulinich TM, et al. Comparison of biological effects of γ-radiation of low and ultra-high dose rate on lymphocytes and cultured human malignant lymphoma cells[J]. Bull Exp Biol Med, 2019, 166(6): 785-787. DOI: 10.1007/s10517-019-04440-0 [14] Nuzzo R. Scientific method: statistical errors[J]. Nature, 2014, 506(7487): 150-152. DOI: 10.1038/506150a [15] Wasserstein RL, Lazar NA. The ASA statement on p-values: context, process, and purpose[J]. Am Stat, 2016, 70(2): 129-133. DOI: 10.1080/00031305.2016.1154108 [16] Amrhein V, Greenland S, McShane B. Scientists rise up against statistical significance[J]. Nature, 2019, 567(7748): 305-307. DOI: 10.1038/d41586-019-00857-9 [17] Hurlbert SH, Levine RA, Utts J. Coup de Grâce for a tough old bull: “statistically significant” expires[J]. Am Stat, 2019, 73(S1): 352-357. DOI: 10.1080/00031305.2018.1543616 [18] 王丽东, 那向杰, 赵杰, 等. 介入放射工作人员血液指标影响因素调查[J]. 中华劳动卫生职业病杂志,2021,39(12):924-928. DOI: 10.3760/cma.j.cn121094-20210511-00248 Wang LD, Na XJ, Zhao J, et al. Investigation on influencing factors of blood indexes of interventional radiology workers[J]. Chin J Ind Hyg Occup Dis, 2021, 39(12): 924-928. DOI: 10.3760/cma.j.cn121094-20210511-00248 [19] 单铁梅, 付丽丽, 王丽东, 等. 电离辐射对放射工作者职业健康的影响[J]. 中国辐射卫生,2021,30(4):402-406. DOI: 10.13491/j.issn.1004-714X.2021.04.003 Shan TM, Fu LL, Wang LD, et al. Effect of ionizing radiation on the occupational health of radiologists[J]. Chin J Radiol Health, 2021, 30(4): 402-406. DOI: 10.13491/j.issn.1004-714X.2021.04.003 [20] 李全开, 张素英, 胡江. 低剂量电离辐射对放射工作人员血像及细胞遗传学影响[J]. 工业卫生与职业病,2011,37(3):155-158. DOI: 10.13692/j.cnki.gywsyzyb.2011.03.003 Li QK, Zhang SY, Hu J. Effect of low-dose ionized radiation on hemogram and cytogenetics of exposed workers[J]. Ind Health Occup Dis, 2011, 37(3): 155-158. DOI: 10.13692/j.cnki.gywsyzyb.2011.03.003 [21] 刘凤君, 许国琼. 低剂量电离辐射对人体外周血象影响流行病学分析[J]. 饮食保健,2018,5(48):5-6. DOI: 10.3969/j.issn.2095-8439.2018.48.006 Liu FJ, Xu GQ. Epidemiological analysis of the effects of low-dose ionizing radiation on human peripheral blood cell analysis[J]. Diet Health, 2018, 5(48): 5-6. DOI: 10.3969/j.issn.2095-8439.2018.48.006 [22] Sia J, Szmyd R, Hau E, et al. Molecular mechanisms of radiation-induced cancer cell death: a primer[J]. Front Cell Dev Biol, 2020, 8: 41. DOI: 10.3389/fcell.2020.00041 [23] Khan MGM, Wang Y. Advances in the current understanding of how low-dose radiation affects the cell cycle[J]. Cells, 2022, 11(3): 356. DOI: 10.3390/cells11030356