成像条件对不同机型PET/CT图像空间分辨率的影响

doi:10.13491/j.issn.1004-714X.2022.03.018

中国辐射卫生

2022, Vol. 31

Issue (3): 350-357 DOI: 10.13491/j.issn.1004-714X.2022.03.018

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成像条件对不同机型PET/CT图像空间分辨率的影响

王瑞, 耿建华, 杜召猛, 张朝坤, 王奕斌, 郑容, 吴宁

国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院核医学科, 北京 100021

Influence of imaging conditions on the spatial resolution of PET/CT images from different models

WANG Rui, GENG Jianhua, DU Zhaomeng, ZHANG Chaokun, WANG Yibin, ZHENG Rong, WU Ning

Department of Nuclear Medicine (PET/CT Center), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021 China

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摘要目的探讨PET/CT成像条件（采集时间、床位重叠、重建矩阵、迭代次数、滤波核、衰减校正）对图像空间分辨率的影响。方法使用GE Discovery Elite 型和GE Discovery ST-16型2种PET/CT设备分别对椭圆柱分辨率模型进行1个和2个床位扫描（List mode模式，采集时间为6 min）；使用临床常用重建条件（Elite型：VPFX-S算法；ST-16型：VUE Point HD 算法）分别按1～6 min/床、不同迭代次数2～10次、滤波核2.0～10.0 mm（Elite型）、不同的重建矩阵以及是否进行衰减校正对图像进行重建；用线源扩展函数的半高宽（FWHM）表示PET重建图像的空间分辨率。结果在临床采集条件下，当采集时间为1 min、2 min、3 min、4 min、5 min、6 min时，中心位置图像空间分辨率FWHM_Elite分别为（4.06 ± 0.08）mm、（4.05 ± 0.20）mm、（4.01 ± 0.01）mm、（4.05 ± 0.07）mm、（4.05 ± 0.03）mm、（4.08 ± 0.06）mm；FWHM_ST-16分别为（5.76 ± 0.12）mm、（5.72 ± 0.11）mm、（5.74 ± 0.09）mm、（5.78 ± 0.05）mm、（5.75 ± 0.09）mm、（5.77 ± 0.07）mm。模体位于1个床位的中心及2个床位重叠处时，中心位置线源FWHM_Elite分别为（4.04 ± 0.01）mm、（4.04 ± 0.01）mm；FWHM_ST-16分别为（5.39 ± 0.19）mm、（5.38 ± 0.07）mm。矩阵为256 × 256、192 × 192、128 × 128时，中心位置FWHM_Elite分别为（4.07 ± 0.18）mm、（4.25 ± 0.10）mm、（4.73 ± 0.08）mm。滤波核2.0 mm、4.0 mm、6.0 mm、8.0 mm、10.0 mm时，中心位置的FWHM_Elite分别为（4.65 ± 0.43）mm、（4.77 ± 0.27）mm、（4.02 ± 0.01）mm、（4.11 ± 0.04）mm、（9.94 ± 0.01）mm。2、4、6、8、10次迭代时，中心位置的FWHM_Elite分别为（4.17 ± 0.27）mm、（4.27 ± 0.21）mm、（4.11 ± 0.05）mm、（4.18 ± 0.04）mm、（4.12 ± 0.06）mm。是否使用衰减校正，中心位置的FWHM_Elite分别为：（4.14 ± 0.01）mm、（4.18 ± 0.08）mm。相同采集时间及床位下，Elite型较ST-16型图像空间分辨率改善约40.57%。结论同一机型矩阵为256 × 256所得到的图像，空间分辨率较另两者高；重建滤波核为6.0 mm时，Elite型图像空间分辨率最好；同一成像条件下，Elite型图像空间分辨率明显好于ST-16型；不同采集时间、床位是否存在重叠，迭代次数以及衰减校正对PET空间分辨率影响不明显。

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关键词 ：正电子发射断层术, 空间分辨率, 成像条件, 模型研究

收稿日期: 2022-02-14

PACS:

R816

通讯作者: 耿建华，Email：gengjean@163.com E-mail: gengjean@163.com

作者简介: 王瑞，女，（1993—），硕士研究生，甘肃通渭人，研究方向：核医学。E-mail：ruiwong8966@126.com

引用本文:

王瑞, 耿建华, 杜召猛, 张朝坤, 王奕斌, 郑容, 吴宁. 成像条件对不同机型PET/CT图像空间分辨率的影响[J]. 中国辐射卫生, 2022, 31(3): 350-357.
WANG Rui, GENG Jianhua, DU Zhaomeng, ZHANG Chaokun, WANG Yibin, ZHENG Rong, WU Ning. Influence of imaging conditions on the spatial resolution of PET/CT images from different models. Chinese Journal of Radiological Health, 2022, 31(3): 350-357.

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http://www.zgfsws.com/CN/10.13491/j.issn.1004-714X.2022.03.018 或 http://www.zgfsws.com/CN/Y2022/V31/I3/350

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