<sup>18</sup>F-FDG PET/CT心肌代谢显像受检者的周围辐射剂量水平

doi:10.13491/j.issn.1004-714X.2022.02.011

中国辐射卫生

2022, Vol. 31

Issue (2): 192-196 DOI: 10.13491/j.issn.1004-714X.2022.02.011

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¹⁸F-FDG PET/CT心肌代谢显像受检者的周围辐射剂量水平

何鑫雨¹, 皮颖斐², 曹雪², 武云云¹, 姜晓燕¹, 贠明凯², 张晓丽², 丁库克¹

1. 中国疾病预防控制中心辐射防护与核安全医学所放射生态学研究室，北京 100088;
2. 首都医科大学附属北京安贞医院核医学科，北京 100029

Ambient radiation of patients undergoing ¹⁸F-FDG PET/CT myocardial metabolism imaging

HE Xinyu¹, PI Yingfei², CAO Xue², WU Yunyun¹, JIANG Xiaoyan¹, YUN Mingkai², ZHANG Xiaoli², DING Kuke¹

1. Department of Radioecology National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088 China;
2. Department of Nuclear Medicine, Beijing AnzhenHospital, Capital Medical University, Beijing 100029 China

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摘要目的探索PET/CT心肌代谢显像受检者周围辐射剂量水平，为保证周围人员辐射安全提供数据支持。方法选取33例行¹⁸F-FDG PET/CT心肌代谢显像患者，在受检者胸部等高位置按照不同体位方向、时间和距离处对其周围剂量当量率进行测量，探索受检者周围剂量当量率的分布规律。结果在相同测量时间和距离下，受检者身体两侧的周围剂量当量率相比正、背面更低。受检者注射¹⁸F-FDG显像剂后，距离体表1 m处正面的周围剂量当量率为13～21 μSv/h，检查结束后降至5～14 μSv/h，平均降低46%。受检者周围剂量当量率随距离（10～300 cm）的增加呈幂函数趋势降低，其幂指数均值为−1.2。结论心肌代谢显像受检者注射药物后周围辐射水平较高，周围剂量当量率随时间和距离增加快速降低，建议心肌代谢显像受检者检查当天避免与他人长时间、近距离接触。

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	何鑫雨
	皮颖斐
	曹雪
	武云云
	姜晓燕
	贠明凯
	张晓丽
	丁库克

关键词 ：核医学, 辐射防护, 周围剂量率, 心肌代谢显像

收稿日期: 2021-09-04

X591

基金资助:国家自然科学基金（31770907）

通讯作者: 丁库克，E-mail：shouding@ccmu.edu.cn E-mail: shouding@ccmu.edu.cn

作者简介: 何鑫雨（1992—），女，山东济南人，研究生，研究方向：辐射防护。E-mail：786239133@qq.com

引用本文:

何鑫雨, 皮颖斐, 曹雪, 武云云, 姜晓燕, 贠明凯, 张晓丽, 丁库克. ¹⁸F-FDG PET/CT心肌代谢显像受检者的周围辐射剂量水平[J]. 中国辐射卫生, 2022, 31(2): 192-196.
HE Xinyu, PI Yingfei, CAO Xue, WU Yunyun, JIANG Xiaoyan, YUN Mingkai, ZHANG Xiaoli, DING Kuke. Ambient radiation of patients undergoing ¹⁸F-FDG PET/CT myocardial metabolism imaging. , 2022, 31(2): 192-196.

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http://www.zgfsws.com/CN/10.13491/j.issn.1004-714X.2022.02.011 或 http://www.zgfsws.com/CN/Y2022/V31/I2/192

[1] 李少林, 王荣福. 核医学[M]. 第八版. 北京: 人民卫生出版社, 2013: 33.
Li SL, Wang RF. Nuclear Medicine[M]. 8th ed. Beijing: People's Medical Publishing House, 2013: 33.
[2] 中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2019概要[J]. 中国循环杂志,2020,35(9):833-854. DOI: 10.3969/j.issn.1000-3614.2020.09.001
The Writing Committee of the Report on Cardiovascular Health and Diseases in China. Report on cardiovascular health and Diseases in China 2019: an Updated Summary[J]. Chin Circul J, 2020, 35(9): 833-854. DOI: 10.3969/j.issn.1000-3614.2020.09.001
[3] 中华医学会核医学分会, 中华医学会心血管病学分会. 核素心肌显像临床应用指南(2018)[J]. 中华心血管病杂志,2019,47(7):519-527. DOI: 10.3760/cma.j.issn.0253-3758.2019.07.003
Society of Nuclear Medicine of Chinese Medical Association, Society of Cardiology of Chinese Medical Association. Guideline for the clinical use of myocardial radionuclide imaging (2018)[J]. Chin J Cardiol, 2019, 47(7): 519-527. DOI: 10.3760/cma.j.issn.0253-3758.2019.07.003
[4] 何作祥, 方纬. 临床价值导向的心血管放射性核素显像[J]. 中华核医学与分子影像杂志,2017,37(5):257-259. DOI: 10.3760/cma.j.issn.2095-2848.2017.05.001
He ZX, Fang W. Patient-centered radionuclide imaging in cardiovascular diseases[J]. Chin J Nucl Med Mol Imag, 2017, 37(5): 257-259. DOI: 10.3760/cma.j.issn.2095-2848.2017.05.001
[5] 鲁瑶, 田毅, 牟甜甜, 等. 门控心肌灌注和心肌代谢显像动态评价远端缺血处理对小型猪心肌梗死模型的保护作用[J]. 中华核医学与分子影像杂志,2021,41(2):104-109. DOI: 10.3760/cma.j.cn321828-20200915-00344
Lu Y, Tian Y, Mou TT, et al. Effects of remote ischemic conditioning in pigs with acute myocardial infarction evaluated by serially gated 99Tc m-MIBI SPECT/CT and ¹⁸F-FDG PET/CT[J]. Chin J Nucl Med Mol Imag, 2021, 41(2): 104-109. DOI: 10.3760/cma.j.cn321828-20200915-00344
[6] 翟光耀, 王建龙, 刘宇扬, 等. ¹⁸F-FDG PET/CT心肌代谢显像评价冠状动脉慢性闭塞性病变存活心肌及与侧枝循环形成的相关性[J]. 心肺血管病杂志,2018,37(5):458-463. DOI: 10.3969/j.issn.1007-5062.2018.05.019
Zhai GY, Wang JL, Liu YY, et al. The correlation study of left ventricular viable myocardium detected by ¹⁸F-FDG PET/CT and coronary collateral circulation in patients with chronic total occlusion lesions[J]. J Cardiovasc and Pulm Dis, 2018, 37(5): 458-463. DOI: 10.3969/j.issn.1007-5062.2018.05.019
[7] 苏玉玲. ¹⁸F-FDG PET/CT显像结束后对周围人群的辐射研究[J]. 中国辐射卫生,2020,29(3):257-259. DOI: 10.13491/j.issn.1004-714X.2020.03.014
Su YL. Radiation study of the surrounding crowd after ¹⁸F-FDG PET/CT imaging[J]. Chin J Radiol Health, 2020, 29(3): 257-259. DOI: 10.13491/j.issn.1004-714X.2020.03.014
[8] 刘伟, 何星. PET-CT诊断项目工作人员受照剂量及相关场所辐射水平测量与分析[J]. 中国辐射卫生,2019,28(3):278-281. DOI: 10.13491/j.issn.1004-714X.2019.03.016
Liu W, He X. Measurement and analysis of radiation dose for staff and radiation level in related places in PET-CT diagnostic project[J]. Chin J Radiol Health, 2019, 28(3): 278-281. DOI: 10.13491/j.issn.1004-714X.2019.03.016
[9] Muzaffar R, Koester E, Frye S, et al. Development of simple methods to reduce the exposure of the public to radiation from patients who have undergone ¹⁸F-FDG PET/CT[J]. J Nucl Med Technol, 2020, 48(1): 63-67. DOI: 10.2967/jnmt.119.233296
[10] Choi BW, Ha S, Sung C, et al. Estimation of effective radiation dose to medical personnel, based on dose rates in patients who have undergone 18F-FDG PET/CT scans[J]. J Nucl Med, 2018, 59(S1): 522
[11] 李宁, 何正中, 杨志, 等. ¹⁸F-FDG和¹⁸F-FET PET-CT检查致受检者辐射剂量研究[J]. 中国辐射卫生,2020,29(1):76-80,84. DOI: 10.13491/j.issn.1004-714X.2020.01.018
Li N, He ZZ, Yang Z, et al. Research on patient dose in ¹⁸F-FDG and ¹⁸F-FET PET-CT examinations[J]. Chin J Radiol Health, 2020, 29(1): 76-80,84. DOI: 10.13491/j.issn.1004-714X.2020.01.018
[12] 翟士桢, 杨志, 杜进. ¹⁸F-FDG的放射性标记、显像原理与临床研究进展[J]. 同位素,2011,24(S1):59-67
Zhai SZ, Yang Z, Du J. Research progress in radiolabeling, imaging mechanism and clinical applications of ¹⁸F-FDG[J]. J Isot, 2011, 24(S1): 59-67
[13] 赵海敏, 朱建国, 杨国仁. PET/CT检查中¹⁸F-FDG所致辐射剂量的研究[J]. 中华核医学杂志,2008,28(5):347-349. DOI: 10.3760/cma.j.issn.2095-2848.2008.05.018
Zhao HM, Zhu JG, Yang GR. Study on radiation dose caused by ¹⁸F-FDG in PET/CT examination[J]. Chin J Nucl Med, 2008, 28(5): 347-349. DOI: 10.3760/cma.j.issn.2095-2848.2008.05.018
[14] 卢桂才, 李鸿成, 姬绪莉. 一例PET-CT受检者体外剂量监测结果及思考[J]. 中国辐射卫生,2013,22(5):552-553. DOI: 10.13491/j.cnki.issn.1004-714X.2013.05.015
Lu GC, Li HC, Ji XL, et al. Results of in vitro dose monitoring in a PET-CT subject and reflections[J]. Chin J Radiol Health, 2013, 22(5): 552-553. DOI: 10.13491/j.cnki.issn.1004-714X.2013.05.015
[15] ICRP. 1990 Recommendations of the International Commission on Radiological Protection[R]. Oxford: International Commission on Radiological Protection, 1991.
[16] 中华人民共和国国家卫生和计划生育委员会. WS 533—2017 临床核医学患者防护要求 [S]. 北京: 中国标准出版社, 2017.
National Health and Family Planning Commission of the People's Republic of China. WS 533—2017 Requirements for patient radiation protection in clinical nuclear medicine[S]. Beijing: Standards Press of China, 2017.
[17] Mountford PJ. Estimation of close contact doses to young infants from surface dose rates on radioactive adults[J]. Nucl Med Commun, 1987, 8(11): 857-863. DOI: 10.1097/00006231-198711000-00002
[18] 黄海潮, 魏伟奇, 翁振乾, 等. PET受检者出院后对公众照射剂量的估算与评价[J]. 中国辐射卫生,2008,17(2):175-176. DOI: 10.3969/j.issn.1004-714X.2008.02.024
Huang HC, Wei WQ, Weng ZQ, et al. Public dose measurement and evaluation from PET subiects after discharged from hospital[J]. Chin J Radiol Health, 2008, 17(2): 175-176. DOI: 10.3969/j.issn.1004-714X.2008.02.024