TOMO-HD图像引导不同部位肿瘤放疗摆位误差的研究

doi:10.13491/j.issn.1004-714X.2021.03.015

中国辐射卫生

2021, Vol. 30

Issue (3): 331-338 DOI: 10.13491/j.issn.1004-714X.2021.03.015

诊断与治疗/论著

本期目录 | 过刊浏览 | 高级检索

TOMO-HD图像引导不同部位肿瘤放疗摆位误差的研究

王银亮, 王慧涛, 郑安平, 孙晓东, 王栋, 刘豪佳, 秦永鹏

安阳市肿瘤医院放射治疗中心，河南安阳 455000

Study on setup errors for different body carcinoma radiotherapy with image guidance in TOMO-HD

WANG Yinliang, WANG Huitao, ZHENG Anping, SUN Xiaodong, WANG Dong, LIU Haojia, QIN Yongpeng

Department of Radiation Oncology, Anyang Tumor Hospital, Anyang 455000 China

摘要
图/表
参考文献
相关文章 (14)

全文: PDF (743 KB) HTML ( )
输出: BibTeX | EndNote (RIS)

摘要目的利用TOMO-HD螺旋加速器的MV级扇形束CT研究头颈部、胸部、腹盆部肿瘤在放疗中的摆位误差，为PTV边界的外扩提供数据支持。方法采用TOMO-HD螺旋断层系统分别对30例头颈部、42例胸部和31例腹盆部肿瘤患者每次放疗前行MV级扇形束CT扫描，系统自动重建图像并与治疗计划CT图像进行配准，获得患者左右（X轴）、头脚（Y轴）、腹背（Z轴）、沿Y轴方向的旋转（Fy）方向的摆位误差。计算出X、Y、Z方向的系统误差（∑）和随机误差（σ）并对摆位误差进行正态性检验，计算出PTV的各方向外扩边界。结果共行2593次扫描，头颈部、胸部、腹盆部患者在X轴、Y轴、Z轴、Fy方向（沿Y轴方向的旋转）的摆位误差（μ ±s）分别为[（-0.31 ±2.16）mm、（1.09 ±3.56）mm、（2.36 ±2.27）mm、(0.29 ±0.96)°]，[（-0.98 ±2.95）mm、（-0.45 ±6.86）mm、（3.79 ±2.47）mm、(0.18 ±0.60)°]和[（-0.86 ±2.85）mm、（-1.59 ±6.91）mm、（5.77 ±2.40）mm、(0.20 ±0.68)°]。头颈部、胸部、腹盆部患者在X轴、Y轴、Z轴方向的系统误差（∑）和随机误差（σ）分别为（1.06 mm和1.84 mm）、（1.93 mm和3.43 mm）、（2.41 mm和2.71 mm），（1.10 mm和2.56 mm）、（3.79 mm和5.46 mm）、（1.38 mm和1.99 mm）和（1.39 mm和0.87 mm）、（4.98 mm和5.69 mm）、（1.19 mm和2.05 mm）。结论根据不同部位的摆位误差频数分布，头颈部、胸部、腹盆部不同部位肿瘤患者的靶区在三维方向上最大运动范围参考值为（5.00, 5.00, 5.00）mm，（6.63，17.25，16.00）mm和（6.49, 16.24, 13.60）mm，推荐以此作为图像引导参考。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	王银亮
	王慧涛
	郑安平
	孙晓东
	王栋
	刘豪佳
	秦永鹏

关键词 ：螺旋断层放疗, 统计分析, 摆位误差, 系统误差, 随机误差, 外扩边界

收稿日期: 2021-01-14

PACS:

R816

通讯作者: 王慧涛(1973-),E-mail:aywht@139.com E-mail: aywht@139.com

作者简介: 王银亮(1986-),男,河南安阳人,硕士研究生,物理师,研究方向:放射治疗的计划设计与放疗技术的应用和质控。E-mail:wyl.145.nm@163.com

引用本文:

王银亮, 王慧涛, 郑安平, 孙晓东, 王栋, 刘豪佳, 秦永鹏. TOMO-HD图像引导不同部位肿瘤放疗摆位误差的研究[J]. 中国辐射卫生, 2021, 30(3): 331-338.
WANG Yinliang, WANG Huitao, ZHENG Anping, SUN Xiaodong, WANG Dong, LIU Haojia, QIN Yongpeng. Study on setup errors for different body carcinoma radiotherapy with image guidance in TOMO-HD. , 2021, 30(3): 331-338.

链接本文:

http://www.zgfsws.com/CN/10.13491/j.issn.1004-714X.2021.03.015 或 http://www.zgfsws.com/CN/Y2021/V30/I3/331

[1] 胡逸民, 杨定宇, 殷蔚伯. 肿瘤放射治疗技术[M]. 北京: 北京医科大学、中国协和医科大学联合出版社, 1999.
Hu YM, Yang DY, Yin WB. Radiation oncology technology[M]. Beijing: Beijing Medical University and China Union Medical College Press, 1999.
[2] Heinzerling JH, Hampton CJ, Robinson M, et al. Use of surface-guided radiation therapy in combination with IGRT for setup and intrafraction motion monitoring during stereotactic body radiation therapy treatments of the lung and abdomen[J]. J Appl Clin Med Phys, 2020, 21(5): 48-55. DOI: 10.1002/acm2.12852
[3] Chu KY, Cooke R, van den Heuvel F, et al. Impact of abdominal compression on setup error and image matching during radical abdominal radiotherapy[J]. Tech Innov Patient Support Radiat Oncol, 2019, 12: 28-33. DOI: 10.1016/j.tipsro.2019.11.003
[4] 李钰, 高岩, 刘世龙, 等. 宫颈癌患者的膀胱充盈度一致性对放疗摆位误差的影响[J]. 中国辐射卫生,2020,29(3):305-308. DOI: 10.13491/j.issn.1004-714X.2020.03.027
Li Y, Gao Y, Liu SL, et al. Effect of consistency of bladder filling volume on set-up errors in radiotherapy for the patients with cervical cancer[J]. Chin J Radiol Health, 2020, 29(3): 305-308. DOI: 10.13491/j.issn.1004-714X.2020.03.027
[5] Woelber JP, Fleiner J, Rau J, et al. Accuracy and usefulness of CBCT in periodontology: a systematic review of the literature[J]. Int J Periodontics Restorative Dent, 2018, 38(2): 289-297. DOI: 10.11607/prd.2751
[6] Tanaka Y, Oita M, Inomata S, et al. Impact of patient positioning uncertainty in noncoplanar intracranial stereotactic radiotherapy[J]. J Appl Clin Med Phys, 2020, 21(2): 89-97. DOI: 10.1002/acm2.12820
[7] Dief S, Veitz-Keenan A, Amintavakoli N, et al. A systematic review on incidental findings in cone beam computed tomography (CBCT) scans[J]. Dentomaxillofac Radiol, 2019, 48(7): 20180396. DOI: 10.1259/dmfr.20180396
[8] Guckenberger M, Meyer J, Vordermark D, et al. Magnitude and clinical relevance of translational and rotational patient setup errors: a cone-beam CT study[J]. Int J Radiat Oncol Biol Phys, 2006, 65(3): 934-942. DOI: 10.1016/j.ijrobp.2006.02.019
[9] Gupta M, Gamre P, Kannan S, et al. Effect of imaging frequency on PTV margins and geographical miss during image guided radiation therapy for prostate cancer[J]. Pract Radiat Oncol, 2018, 8(2): e41-e47. DOI: 10.1016/j.prro.2017.09.010
[10] 戴建荣, 胡逸民. 图像引导放疗的实现方式[J]. 中华放射肿瘤学杂志,2006,15(2):132-135. DOI: 10.3760/j.issn:1004-4221.2006.02.019
Dai JR, Hu YM. The methods of image-guided radiation therapy[J]. Chin J Radiat Oncol, 2006, 15(2): 132-135. DOI: 10.3760/j.issn:1004-4221.2006.02.019
[11] 于金明, 袁双虎. 图像引导放射治疗研究及其发展[J]. 中华肿瘤杂志,2006,28(2):81-83. DOI: 10.3760/j.issn:0253-3766.2006.02.001
Yu JM, Yuan SH. Research and advancement of image-guided radiotherapy[J]. Chin J Radiat Oncol, 2006, 28(2): 81-83. DOI: 10.3760/j.issn:0253-3766.2006.02.001
[12] 叶程伟, 周继丹, 商强, 等. 基于光学表面成像与锥形束CT结合的综合引导模式在头颈部肿瘤精确放疗中的研究[J]. 中国辐射卫生,2019,28(3):346-350. DOI: 10.13491/j.issn.1004-714x.2019.03.034
Ye CW, Zhou JD, Shang Q, et al. Comprehensive guidance model based on optical surface imaging combined with cone beam CT in head and neck tumors accurate radiation therapy[J]. Chin J Radiol Health, 2019, 28(3): 346-350. DOI: 10.13491/j.issn.1004-714x.2019.03.034
[13] Ding Y, Ma PP, Li W, et al. Effect of surgical mask on setup error in head and neck radiotherapy[J]. Technol Cancer Res Treat, 2020, 19: 153303382097402. DOI: 10.1177/1533033820974021
[14] Patni N, Burela N, Pasricha R, et al. Assessment of three-dimensional setup errors in image-guided pelvic radiotherapy for uterine and cervical cancer using kilovoltage cone-beam computed tomography and its effect on planning target volume margins[J]. J Cancer Res Ther, 2017, 13(1): 131-136. DOI: 10.4103/0973-1482.199451
[15] 高璇, 李克新, 鞠永健, 等. 前列腺癌患者调强放疗中的摆位误差及其对剂量分布影响分析[J]. 中国辐射卫生,2018,27(3):228-230, 251. DOI: 10.13491/j.issn.1004-714x.2018.03.010
Gao X, Li KX, Ju YJ, et al. The study about the setup error and its effect on dose distribution in IMRT for prostate cancer patients[J]. Chin J Radiol Health, 2018, 27(3): 228-230, 251. DOI: 10.13491/j.issn.1004-714x.2018.03.010
[16] Onal C, Dolek Y, Ozdemir Y. The impact of androgen deprivation therapy on setup errors during external beam radiation therapy for prostate cancer[J]. Et Al, 2017, 193(6): 472-482. DOI: 10.1007/s00066-017-1131-z
[17] 刘吉平, 孙晓江, 狄小云, 等. 利用锥形束CT图像分析胸部调强放疗的摆位误差[J]. 中国辐射卫生,2013,22(2):182-184. DOI: 10.13491/j.cnki.issn.1004-714x.2013.02.054
Liu JP, Sun XJ, Di XY, et al. Analysis of setup errors for thoracic carcinoma radiotherapy with cone-beam CT-based image guidance[J]. Chin J Radiol Health, 2013, 22(2): 182-184. DOI: 10.13491/j.cnki.issn.1004-714x.2013.02.054
[18] 王志伟, 段继梅, 岳麒, 等. 220例肿瘤患者HT靶区几何学不确定性分析[J]. 中华放射肿瘤学杂志,2014,23(5):415-417. DOI: 10.3760/cma.j.issn.1004-4221.2014.05.013
Wang ZW, Duan JM, Yue Q, et al. Analysis geometrical uncertainties of 220 cases in helical tomotherapy (HT)[J]. Chin J Radiat Oncol, 2014, 23(5): 415-417. DOI: 10.3760/cma.j.issn.1004-4221.2014.05.013
[19] Selvan KT, Padma G, Revathy MK, et al. Dosimetric effect of rotational setup errors in single-isocenter volumetric-modulated arc therapy of multiple brain metastases[J]. J Med Phys, 2019, 44(2): 84-90. DOI: 10.4103/jmp.JMP_103_18
[20] Delishaj D, Ursino S, Pasqualetti F, et al. Set-up errors in head and neck cancer treated with IMRT technique assessed by cone-beam computed tomography: a feasible protocol[J]. Radiat Oncol J, 2018, 36(1): 54-62. DOI: 10.3857/roj.2017.00493
[21] Xiao AN, Jutzy J, Hubert G, et al. A study of the dosimetric impact of daily setup variations measured with cone-beam CT on three-dimensional conformal radiotherapy for early-stage breast cancer delivered in the prone position[J]. J Appl Clin Med Phys, 2020, 21(12): 146-154. DOI: 10.1002/acm2.13080
[22] 胡逸民. 肿瘤放射物理学[M]. 北京: 原子能出版社, 1999.
Hu YM. Radiation oncology physics[M]. Beijing: Atomic Press, 1999.