[1] Fleming A M, Ding Y, Burrows C J. Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair[J]. Proc Natl Acad Sci USA, 2017, 114(10): 2604-2609 [2] Fontugne J, Steeq HV, Wit JD. DNA Damage Repair[M]. 2018. [3] Mouw K W, Goldberg M S, Konstantinopoulos P A, et al. DNA damage and repair biomarkers of immunotherapy response[J]. Cancer Discov, 2017, 7(7): 675-693 [4] Arjumand W, Asiaf A, Ahmad S T. Noncoding RNAs in DNA damage response: opportunities for cancer therapeutics[J]. Methods Mol Biol, 2018, 1699: 3-21 [5] Turgeon MO, Perry Nicholas JS, George P, et al. DNA Damage, Repair, and Cancer Metabolism[J]. Front in Oncol, 2018, 8(6): 15-20 [6] Shubassi G, Robert T, Vanoli F, et al. Acetylation: a novel link between double-strand break repair and autophagy[J]. Cancer Res, 2012, 72(6): 1332-1335 [7] 李梅, 刘梦雅, 王新钢, 等. NHEJ通路相关基因在电离辐射所致脑损伤中的表达情况研究[J]. 中国辐射卫生,2019,28(3):223-227 [8] Bharti S K, Brosh R M Jr. Fine-tuning DNA repair by protein acetylation[J]. Cell Cycle, 2016, 15(15): 1952-1953 [9] Song J, Kemp M G, Choi J H. Detection of the excised, damage-containing oligonucleotide products of nucleotide excision repair in human cells[J]. Photochem Photobiol, 2017, 93(1): 192-198 [10] Song X, Wang S M, Hong X, et al. Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer[J]. Sci Rep, 2017, 7(1): 11785 [11] Muñoz M J, Nieto Moreno N, Giono L E, et al. Major roles for pyrimidine dimers, nucleotide excision repair, and ATR in the alternative splicing response to UV irradiation[J]. Cell Rep, 2017, 18(12): 2868-2879 [12] Rupp W D. Early days of DNA repair: discovery of nucleotide excision repair and homology-dependent recombinational repair[J]. Yale J Biol Med, 2013, 86(4): 499-505 [13] Pollet M, Shaik S, Mescher M, et al. The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis[J]. Cell Death Differ, 2018, 25(10): 1823-1836 [14] Helleday T, Petermann E, Lundin C, et al. DNA repair pathways as targets for cancer therapy[J]. Nat Rev Cancer, 2008, 8(3): 193-204 [15] Kusakabe M, Onishi Y, Tada H, et al. Mechanism and regulation of DNA damage recognition in nucleotide excision repair[J]. Genes Environ, 2019, 41: 2 [16] Kim B J, Kim B R, Kook Y H, et al. Role of the DNA mismatch repair gene MutS4 in driving the evolution of Mycobacterium yongonense type I via homologous recombination[J]. Front Microbiol, 2017, 8(3): 2578-2585 [17] Liu J Y, Qian C Y, Gao Y F, et al. Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients[J]. Chin J Cancer, 2017, 36(12): 267-273 [18] Smyth E C, Wotherspoon A, Peckitt C, et al. Mismatch repair deficiency, microsatellite instability, and survival: an exploratory analysis of the medical research council adjuvant gastric infusional chemotherapy (MAGIC) trial[J]. JAMA Oncol, 2017, 3(9): 1197-1203 [19] Hsieh P, Yamane K. DNA mismatch repair: molecular mechanism, cancer, and ageing[J]. Mech Ageing Dev, 2008, 129(7/8): 391-407 [20] Naboush A, Roman C A, Shapira I. Immune checkpoint inhibitors in malignancies with mismatch repair deficiency: a review of the state of the current knowledge[J]. J Investig Med, 2017, 65(4): 754-758 [21] Ranjha L, Howard S M, Cejka P. Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes[J]. Chromosoma, 2018, 127(2): 187-214 [22] Klement K, Goodarzi A A. Analyzing heterochromatic DNA double strand break (DSB) repair in response to ionizing radiation[J]. Methods Mol Biol, 2017, 1599: 303-315 [23] Sibanda B L, Chirgadze D Y, Ascher D B, et al. DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair[J]. Science, 2017, 355(6324): 520-524 [24] Saha J, Wang S Y, Davis A J. Examining DNA double-strand break repair in a cell cycle-dependent manner[J]. Meth Enzymol, 2017, 591: 97-118 [25] Đermić E, Zahradka D, Vujaklija D, et al. 3'-terminated overhangs regulate DNA double-strand break processing in Escherichia coli[J]. G3 (Bethesda), 2017, 7(9): 3091-3102 [26] Adkins N L, Swygert S G, Kaur P, et al. Nucleosome-like, single-stranded DNA (ssDNA)-histone octamer complexes and the implication for DNA double strand break repair[J]. J Biol Chem, 2017, 292(13): 5271-5281 [27] 董怡萍, 张丹, 韩苏夏. DNA损伤修复机制的研究进展[J]. 中华放射肿瘤学杂志,2017,26(9):1103-1108 [28] Dahal S, Dubey S, Raghavan S C. Homologous recombination-mediated repair of DNA double-strand breaks operates in mammalian mitochondria[J]. Cell Mol Life Sci, 2018, 75(9): 1641-1655 [29] Yin L L, Liu Y H, Peng Y C, et al. PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells[J]. J Exp Clin Cancer Res, 2018, 37(1): 153-168 [30] Collis S J, Tighe A, Scott S D, et al. Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells[J]. Nucleic Acids Res, 2001, 29(7): 1534-1538 [31] Belenkov A I, Paiement J P, Panasci L C, et al. An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents[J]. Cancer Res, 2002, 62(20): 5888-5896 [32] Mullenders L H F. Solar UV damage to cellular DNA: from mechanisms to biological effects[J]. Photochem Photobiol Sci, 2018, 17(12): 1842-1852 [33] Kysela B P, Michael B D, Arrand J E. Relative contributions of levels of initial DNA damage and repair of double strand breaks to the ionizing radiation-sensitive phenotype of the Chinese hamster cell mutant, XR-V15B. Part I. X-rays[J]. Int J Radiat Biol, 1993, 63(5): 609-616 [34] 王艳俊, 蒋永新, 刘姗, 等. 肿瘤放疗增敏药物新靶点[J]. 国际肿瘤学杂志,2017,44(2):129-132 [35] 马晓洁, 谭榜宪. 辐射损伤修复应答与放射增敏[J]. 肿瘤预防与治疗,2010,23(3):256-258, 243 [36] Wu R, Forget M A, Chacon J, et al. Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook[J]. Cancer J, 2012, 18(2): 160-175 [37] Li J J, Li H W, Zhan D C, et al. Niclosamide sensitizes nasopharyngeal carcinoma to radiation by downregulating Ku70/80 expression[J]. J Cancer, 2018, 9(4): 736-744 [38] 王麟华, 吴玉梅, 于新平. DNA损伤修复在宫颈癌放疗敏感性中的研究进展[J]. 解放军预防医学杂志,2019,17(8):122-126 [39] Lin Y F, Shih H Y, Shang Z F, et al. PIDD mediates the association of DNA-PKcs and ATR at stalled replication Forks to facilitate the ATR signaling pathway[J]. Nucleic Acids Res, 2018, 46(4): 1847-1859 [40] Verhagen C V, de Haan R, Hageman F, et al. Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells[J]. Radiother Oncol, 2015, 116(3): 358-365 [41] Jiang Y H, Liu Y M, Hu H. Studies on DNA damage repair and precision radiotherapy for breast cancer[J]. Adv Exp Med Biol, 2017, 1026: 105-123 [42] Mahamud O, So J, Chua M L K, et al. Targeting DNA repair for precision radiotherapy: Balancing the therapeutic ratio[J]. Curr Probl Cancer, 2017, 41(4): 265-272 [43] Khosravi R, Maya R, Gottlieb T, et al. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage[J]. Proc Natl Acad Sci USA, 1999, 96(26): 14973-14977 [44] 马承贤, 蔡梦娇, 韩苏夏. DNA损伤修复与肿瘤放射敏感性的研究进展[J]. 医学版,2020,41(1):1-6 [45] 徐维强, 唐庚, 刘纯岩, 等. 辐射对沉默ATRX的H460细胞增殖以及DNA损伤修复的影响[J]. 中国辐射卫生,2019,28(4):364-367 [46] Karlin J, Allen J, Ahmad S F, et al. Orally bioavailable and blood-brain barrier-penetrating ATM inhibitor (AZ32) radiosensitizes intracranial gliomas in mice[J]. Mol Cancer Ther, 2018, 17(8): 1637-1647 [47] Durant S T, Zheng L, Wang Y C, et al. The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models[J]. Sci Adv, 2018, 4(6): 1719-1725