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| [Ca2+] i in Exterior of Cells Effected on Apoptosis of HL-60 Cells Induced by Irradiation |
| HE Zi-yi, MENG Qing-yong |
| Analysis Center of Guang dong Medical College 524023 |
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Abstract Objective To investigate of the different[Ca2+] i in exterior of cells promotion function on apoptosis of HL-60 cells induced by irradiation. Methods To put ration dose 32P and different[Ca2+] i into culture of HL-60 and measure the apoptosis rate with FCM after 24 and 48 hours. Result Apoptosis rate increased with the increase of[Ca2+] i which shows an obvious function to promote apoptosis, r24=0.9001 (P=0.0145);r48=0.9343 (P=0.0063).Conclusion [Ca2+] i in exterior of cells has a obvious function in promoteing apoptosis induced by irradiation.
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Received: 29 April 2005
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